PTPDC1 and AATK

Number of citations of the paper that reports this interaction (PubMedID 28065597)
37

Data Source:
BioGRID (two hybrid)

		PTPDC1	AATK
Description		protein tyrosine phosphatase domain containing 1	apoptosis associated tyrosine kinase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cellular_component Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity	Protein Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Protein Serine Kinase Activity
	Biological Process	Peptidyl-tyrosine Dephosphorylation Cilium Assembly	Protein Phosphorylation Brain Development Biological_process Peptidyl-tyrosine Autophosphorylation
Pathways
Drugs
Diseases
GWAS		Birth weight ( 31043758) Esophageal adenocarcinoma ( 24121790) Heel bone mineral density ( 30598549) Height ( 20881960) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Parkinson's disease ( 26227905) Type 2 diabetes ( 30054458) Waist-hip ratio ( 25673412) Waist-to-hip ratio adjusted for body mass index ( 25673412)	Age at first sexual intercourse ( 34211149) Appendicular lean mass ( 33097823) Beef consumption ( 32066663) Lymphocyte percentage of white cells ( 32888494) Neuroticism ( 29255261) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Obesity-related traits ( 23251661) Serum uric acid levels in response to allopurinol in gout ( 25676789)
Interacting Genes		8 interacting genes: AATK CRKL ERBB3 ERBB4 LMTK2 MAPK1 MID2 TEX11	43 interacting genes: BDKRB2 CDC14A CDC25B CDK5 DUSP1 DUSP14 DUSP29 DUSP5 DUSP6 DUSP9 ERBB2 EYA2 EYA4 ILKAP MTMR10 MTMR6 MTMR8 MTMR9 PPM1A PPM1B PPM1F PPM1K PPM1M PPP1CA PPP1CB PPP1CC PPP3CA PPP3CB PTEN PTPDC1 PTPN11 PTPN12 PTPN18 PTPN20 PTPN6 PTPN7 PTPRR SBF1 STK39 STYX TAB1 TEPSIN TPTE2
Entrez ID		138639	9625
HPRD ID		06689	05591
Ensembl ID		ENSG00000158079	ENSG00000181409
Uniprot IDs		A0A087WTF0 A2A3K4 A8K0X7	H7C175 Q6ZMQ8
PDB IDs
Enriched GO Terms of Interacting Partners?
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