CMTM5 and LRRC4C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CMTM5	LRRC4C
Description		CKLF like MARVEL transmembrane domain containing 5	leucine rich repeat containing 4C
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation	Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) High myopia ( 31816047) Iris color (L* coordinate) ( 30895295) Mastocytosis (KIT D816V positive) ( 33421400) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Pediatric central nervous system tumors (early onset)(pleiotropy) ( 33226468) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)
Interacting Genes		131 interacting genes: AACS ABHD4 ACSF2 ACSM1 ALDH18A1 APOA1 APOA4 APOA5 AQP6 ARFIP1 ARFIP2 ARMC9 BIK BNIP3 CAPNS2 CD160 CD40 CD79A CLDN7 COQ8A CPLX1 CPLX4 CREB3 CYP1A1 DDA1 DHRSX ECPAS ELOVL4 ERGIC3 FAM114A1 FARS2 FCGR2A FCRL3 FERMT2 FFAR2 FNDC9 GAD1 GAD2 GJB1 GLTP GOLGA2P10 GPX8 GTF3C1 HNRNPK HSD17B13 JAGN1 JOSD2 KASH5 KCNJ6 KCNK5 KIR3DL3 LEUTX LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MCEMP1 MCFD2 MEOX2 MFF MGST3 MIEF1 MRM1 MRRF MTERF3 MTIF3 MYG1 NDRG4 NFU1 NTAQ1 PBX3 PCNA PIMREG PITPNC1 PLIN3 PNPO POLL PPIF PPP2R3C PSCA PTPN9 RBFA REEP2 RETREG3 RHBDD1 RMDN2 RNF185 RSRC2 RUSF1 SAR1A SCARA5 SDCBP SGCB SH3GL1 SH3GLB1 SHMT2 SLC10A6 SLC18A2 SLC30A4 SLC35C2 SLC7A14 SNX1 SPATA8 SPG21 SSX3 SSX5 STING1 STOM SUCLA2 SYNE4 SYT16 TBRG4 THAP4 TIMM44 TLCD4 TMED8 TMEM139 TMEM14B TMEM35A TMEM80 TMF1 TPD52L3 TSPAN31 TTPA TUBB TUFM VARS2 ZNF391 ZNF599	29 interacting genes: AGTRAP BDKRB1 BMP10 BRICD5 CLDN19 CLEC1A CLEC4G CMTM5 CREB3L4 DOLK DRAM1 EMP3 GJB2 LEPROTL1 LHFPL5 MIP NTNG1 PGAP2 PLP2 SERTM1 SMIM1 SNAP47 STX5 TRAF6 TWSG1 VEZT VSTM1 WHRN YIPF6
Entrez ID		116173	57689
HPRD ID		06986	12303
Ensembl ID		ENSG00000166091	ENSG00000148948
Uniprot IDs		Q96DZ9	Q4JIV9 Q4JIW0 Q9HCJ2
PDB IDs			3ZYJ
Enriched GO Terms of Interacting Partners?
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