CMTM5 and RNF185

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		CMTM5	RNF185
Description		CKLF like MARVEL transmembrane domain containing 5	ring finger protein 185
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Integral Component Of Membrane	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Cytokine Activity Protein Binding	Protein Binding Ubiquitin Binding Ubiquitin-like Protein Conjugating Enzyme Binding Protein-containing Complex Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Chemotaxis Signal Transduction Negative Regulation Of Myoblast Differentiation	Ubiquitin-dependent Protein Catabolic Process Autophagy Ubiquitin-dependent ERAD Pathway ERAD Pathway Protein Autoubiquitination Transmembrane Transport ER-associated Misfolded Protein Catabolic Process Positive Regulation Of ERAD Pathway Endoplasmic Reticulum Mannose Trimming
Pathways			ABC-family proteins mediated transport Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Fish- and plant-related diet ( 32066663) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Waist circumference ( 28552196) White blood cell count ( 32888494)
Interacting Genes		131 interacting genes: AACS ABHD4 ACSF2 ACSM1 ALDH18A1 APOA1 APOA4 APOA5 AQP6 ARFIP1 ARFIP2 ARMC9 BIK BNIP3 CAPNS2 CD160 CD40 CD79A CLDN7 COQ8A CPLX1 CPLX4 CREB3 CYP1A1 DDA1 DHRSX ECPAS ELOVL4 ERGIC3 FAM114A1 FARS2 FCGR2A FCRL3 FERMT2 FFAR2 FNDC9 GAD1 GAD2 GJB1 GLTP GOLGA2P10 GPX8 GTF3C1 HNRNPK HSD17B13 JAGN1 JOSD2 KASH5 KCNJ6 KCNK5 KIR3DL3 LEUTX LMNA LMO2 LNX1 LRRC4C LRRC59 MCEE MCEMP1 MCFD2 MEOX2 MFF MGST3 MIEF1 MRM1 MRRF MTERF3 MTIF3 MYG1 NDRG4 NFU1 NTAQ1 PBX3 PCNA PIMREG PITPNC1 PLIN3 PNPO POLL PPIF PPP2R3C PSCA PTPN9 RBFA REEP2 RETREG3 RHBDD1 RMDN2 RNF185 RSRC2 RUSF1 SAR1A SCARA5 SDCBP SGCB SH3GL1 SH3GLB1 SHMT2 SLC10A6 SLC18A2 SLC30A4 SLC35C2 SLC7A14 SNX1 SPATA8 SPG21 SSX3 SSX5 STING1 STOM SUCLA2 SYNE4 SYT16 TBRG4 THAP4 TIMM44 TLCD4 TMED8 TMEM139 TMEM14B TMEM35A TMEM80 TMF1 TPD52L3 TSPAN31 TTPA TUBB TUFM VARS2 ZNF391 ZNF599	30 interacting genes: APP CGAS CMTM5 CYB561A3 DVL2 FAM241B MALL MS4A13 MTNR1B MYADML2 NIPAL4 TMEM147 TMEM19 TMEM86A UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2V1 UBE2W USP21 YIPF2 YIPF4 YIPF6
Entrez ID		116173	91445
HPRD ID		06986	08790
Ensembl ID		ENSG00000166091	ENSG00000138942
Uniprot IDs		Q96DZ9	A0A024R1F5 A0A024R1H4 Q96GF1
PDB IDs
Enriched GO Terms of Interacting Partners?
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