LRRC4C and PGAP2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LRRC4C	PGAP2
Description		leucine rich repeat containing 4C	post-GPI attachment to proteins 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Membrane Integral Component Of Membrane Schaffer Collateral - CA1 Synapse Glutamatergic Synapse Integral Component Of Postsynaptic Density Membrane	Golgi Membrane Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Cell Adhesion Molecule Binding Cell-cell Adhesion Mediator Activity	Protein Binding
	Biological Process	Regulation Of Axonogenesis Modulation Of Chemical Synaptic Transmission Synaptic Membrane Adhesion	GPI Anchor Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Cerebellum cortex volume ( 31530798) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cerebrospinal fluid p-tau levels ( 29274321) Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) General risk tolerance (MTAG) ( 30643258) High myopia ( 31816047) Iris color (L* coordinate) ( 30895295) Mastocytosis (KIT D816V positive) ( 33421400) Mosquito bite size ( 28199695) Myopia ( 27182965) Osteoporosis-related phenotypes ( 20548944) Pediatric central nervous system tumors (early onset)(pleiotropy) ( 33226468) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Survival in colorectal cancer ( 26586795) Temperament (bipolar disorder) ( 22365631)	Malaria ( 31844061)
Interacting Genes		29 interacting genes: AGTRAP BDKRB1 BMP10 BRICD5 CLDN19 CLEC1A CLEC4G CMTM5 CREB3L4 DOLK DRAM1 EMP3 GJB2 LEPROTL1 LHFPL5 MIP NTNG1 PGAP2 PLP2 SERTM1 SMIM1 SNAP47 STX5 TRAF6 TWSG1 VEZT VSTM1 WHRN YIPF6	31 interacting genes: AMIGO1 ARL13B BIK CD79A CGRRF1 CISD2 CLDN7 CLSTN3 COMT CPLX4 CREB3L1 CYSRT1 ERGIC3 F11R FAM209A FNDC9 GJA5 GJA8 GJB5 GPR152 GPX8 KASH5 KRTAP10-3 KRTAP10-9 LRRC4C PDZK1IP1 SSMEM1 STX1A TMEM52B TMEM9 TMPRSS2
Entrez ID		57689	27315
HPRD ID		12303	17016
Ensembl ID		ENSG00000148948	ENSG00000148985
Uniprot IDs		Q4JIV9 Q4JIW0 Q9HCJ2	A0A024RCC6 A0A024RCD5 A0A0A0MS75 A0A0S2Z568 A8MYS5 B7Z2X5 H0YDQ4 Q9UHJ9
PDB IDs		3ZYJ
Enriched GO Terms of Interacting Partners?
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