LRRC4C and GJB2

  • Number of citations of the paper that reports this interaction (PubMedID 32296183)
  • 86
  • Data Source:
  • BioGRID (two hybrid)

LRRC4C

GJB2

Description leucine rich repeat containing 4C gap junction protein beta 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576)
  • Cerebellum cortex volume ( 31530798)
  • Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835)
  • Cerebrospinal fluid p-tau levels ( 29274321)
  • Diastolic blood pressure response to thiazide and thiazide-like diuretics in hypertension ( 31754133)
  • Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189)
  • General risk tolerance (MTAG) ( 30643258)
  • High myopia ( 31816047)
  • Iris color (L* coordinate) ( 30895295)
  • Mastocytosis (KIT D816V positive) ( 33421400)
  • Mosquito bite size ( 28199695)
  • Myopia ( 27182965)
  • Osteoporosis-related phenotypes ( 20548944)
  • Pediatric central nervous system tumors (early onset)(pleiotropy) ( 33226468)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Refractive error ( 32231278)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
  • Smoking status (ever vs never smokers) ( 30643258)
  • Spherical equivalent or myopia (age of diagnosis) ( 29808027)
  • Survival in colorectal cancer ( 26586795)
  • Temperament (bipolar disorder) ( 22365631)
  • Facial emotion recognition (happy faces) ( 28608620)
Interacting Genes 29 interacting genes: AGTRAP BDKRB1 BMP10 BRICD5 CLDN19 CLEC1A CLEC4G CMTM5 CREB3L4 DOLK DRAM1 EMP3 GJB2 LEPROTL1 LHFPL5 MIP NTNG1 PGAP2 PLP2 SERTM1 SMIM1 SNAP47 STX5 TRAF6 TWSG1 VEZT VSTM1 WHRN YIPF6 44 interacting genes: AMIGO1 APLNR AQP6 ARL13B CAV1 CD14 CNST CREB3 EBP ERGIC3 FAM209A FFAR2 GJA5 GJA8 GJB1 GJB6 GPR152 GPR42 HSD17B13 KCNK5 KLRC1 LHFPL5 LMNA LRRC4C MFSD6 MS4A6E NGLY1 PEX12 PLEKHB2 SAR1A SHISAL1 SLC18A1 SLC30A2 SSMEM1 TBXA2R TEX29 TIMMDC1 TLCD4 TM2D2 TMEM106A TMEM237 TMEM31 TMX2 TRHR
Entrez ID 57689 2706
HPRD ID 12303 00413
Ensembl ID ENSG00000148948 ENSG00000165474
Uniprot IDs Q4JIV9 Q4JIW0 Q9HCJ2 H9U1J4 P29033
PDB IDs 3ZYJ 1XIR 2ZW3 3IZ1 3IZ2 5ER7 5ERA 5KJ3 5KJG 6UVR 6UVS 6UVT
Enriched GO Terms of Interacting Partners?
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