CLP1 and DAGLB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLP1	DAGLB
Description		cleavage factor polyribonucleotide kinase subunit 1	diacylglycerol lipase beta
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Cytosol MRNA Cleavage Factor Complex	Nucleoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Postsynaptic Membrane
	Molecular Function	Protein Binding ATP Binding Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity Polydeoxyribonucleotide Kinase Activity Polyribonucleotide 5'-hydroxyl-kinase Activity	Triglyceride Lipase Activity Protein Binding Lipase Activity Metal Ion Binding Acylglycerol Lipase Activity
	Biological Process	MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation RNA Processing Phosphorylation Cerebellar Cortex Development Targeting Of MRNA For Destruction Involved In RNA Interference MRNA 3'-end Processing SiRNA Loading Onto RISC Involved In RNA Interference	Prostaglandin Biosynthetic Process G Protein-coupled Glutamate Receptor Signaling Pathway Neuroblast Proliferation Positive Regulation Of Triglyceride Catabolic Process Lipid Catabolic Process Arachidonic Acid Metabolic Process Neurogenesis Neurotransmitter Biosynthetic Process Regulation Of Inflammatory Response Endocannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Arachidonate production from DAG
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Neuroticism ( 29255261) Schizophrenia ( 25056061 29483656)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Body mass index ( 26426971) Coronary artery disease ( 29212778) HDL cholesterol ( 24097068 30275531) HDL cholesterol levels ( 32203549 28334899) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817) Inflammatory bowel disease ( 28067908) Lymphocyte percentage of white cells ( 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252) Red cell distribution width ( 32888494) Ulcerative colitis ( 28067908) Waist-hip ratio and HDL-C (pairwise) ( 33619380) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)
Interacting Genes		17 interacting genes: APP CEP164 CPSF3 CREB3 DAGLB FGF16 FTO HCFC1 MEOX2 MESD NUDT21 PCMT1 PRR3 PSMB5 SNF8 TSEN54 YJU2B	4 interacting genes: CLP1 NBPF19 NOTCH2NLA PISD
Entrez ID		10978	221955
HPRD ID		16382	17324
Ensembl ID		ENSG00000172409	ENSG00000164535
Uniprot IDs		Q92989	Q8NCG7
PDB IDs
Enriched GO Terms of Interacting Partners?
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