CLP1 and PCMT1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		CLP1	PCMT1
Description		cleavage factor polyribonucleotide kinase subunit 1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component	TRNA-intron Endonuclease Complex Nucleus Nucleoplasm Cytosol MRNA Cleavage Factor Complex	Cytoplasm Cytosol Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding ATP Binding Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity Polydeoxyribonucleotide Kinase Activity Polyribonucleotide 5'-hydroxyl-kinase Activity	Protein-L-isoaspartate (D-aspartate) O-methyltransferase Activity Protein Binding Cadherin Binding
	Biological Process	MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation RNA Processing Phosphorylation Cerebellar Cortex Development Targeting Of MRNA For Destruction Involved In RNA Interference MRNA 3'-end Processing SiRNA Loading Onto RISC Involved In RNA Interference	Protein Methylation Protein Repair
Pathways		tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Protein repair
Drugs			S-adenosyl-L-homocysteine
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Neuroticism ( 29255261) Schizophrenia ( 25056061 29483656)	Brain morphology (MOSTest) ( 32665545) Serum metabolite levels ( 33031748) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		17 interacting genes: APP CEP164 CPSF3 CREB3 DAGLB FGF16 FTO HCFC1 MEOX2 MESD NUDT21 PCMT1 PRR3 PSMB5 SNF8 TSEN54 YJU2B	13 interacting genes: AGTR1 APOA1 APOE CCR2 CHD3 CLP1 CREBBP CYSLTR2 DLG4 IQCB1 RPIA TAAR1 VKORC1
Entrez ID		10978	5110
HPRD ID		16382	08908
Ensembl ID		ENSG00000172409	ENSG00000120265
Uniprot IDs		Q92989	A0A0A0MRJ6 A0A3F2YNX8 B7Z972 F6S8N6 P22061
PDB IDs			1I1N 1KR5
Enriched GO Terms of Interacting Partners?
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