DAGLB and PISD

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		DAGLB	PISD
Description		diacylglycerol lipase beta	phosphatidylserine decarboxylase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Membrane Postsynaptic Membrane	Nucleus Mitochondrion Integral Component Of Mitochondrial Inner Membrane
	Molecular Function	Triglyceride Lipase Activity Protein Binding Lipase Activity Metal Ion Binding Acylglycerol Lipase Activity	Phosphatidylserine Decarboxylase Activity
	Biological Process	Prostaglandin Biosynthetic Process G Protein-coupled Glutamate Receptor Signaling Pathway Neuroblast Proliferation Positive Regulation Of Triglyceride Catabolic Process Lipid Catabolic Process Arachidonic Acid Metabolic Process Neurogenesis Neurotransmitter Biosynthetic Process Regulation Of Inflammatory Response Endocannabinoid Signaling Pathway Retrograde Trans-synaptic Signaling By Endocannabinoid	Phosphatidylethanolamine Biosynthetic Process Regulation Of Mitochondrion Organization Protein Autoprocessing Mitochondrial Protein Catabolic Process
Pathways		Arachidonate production from DAG	Synthesis of PE
Drugs			Phosphatidyl serine
Diseases
GWAS		Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Body mass index ( 26426971) Coronary artery disease ( 29212778) HDL cholesterol ( 24097068 30275531) HDL cholesterol levels ( 32203549 28334899) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) High density lipoprotein cholesterol levels ( 33339817) Inflammatory bowel disease ( 28067908) Lymphocyte percentage of white cells ( 27863252) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252) Red cell distribution width ( 32888494) Ulcerative colitis ( 28067908) Waist-hip ratio and HDL-C (pairwise) ( 33619380) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226)	Age-related hearing impairment ( 24939585) Fish- and plant-related diet ( 32066663) Intelligence ( 22449649) Oily fish consumption ( 32066663) Paclitaxel-induced neuropathy ( 23776197) Pork consumption ( 32066663)
Interacting Genes		4 interacting genes: CLP1 NBPF19 NOTCH2NLA PISD	4 interacting genes: BRCA1 CIDEB DAGLB DHX29
Entrez ID		221955	23761
HPRD ID		17324	17854
Ensembl ID		ENSG00000164535	ENSG00000241878
Uniprot IDs		Q8NCG7	A0A024R1K5 Q9UG56
PDB IDs
Enriched GO Terms of Interacting Partners?
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