PTBP2 and EIF5A2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		PTBP2	EIF5A2
Description		polypyrimidine tract binding protein 2	eukaryotic translation initiation factor 5A2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body	Nuclear Pore Endoplasmic Reticulum Membrane Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding MRNA Binding	Translation Elongation Factor Activity Protein Binding Ribosome Binding
	Biological Process	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	Translational Frameshifting Spermatogenesis Positive Regulation Of Cell Proliferation Polyamine Homeostasis Protein Transport Positive Regulation Of Translational Elongation Positive Regulation Of Translational Termination MRNA Transport
Pathways			Hypusine synthesis from eIF5A-lysine
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)	C-reactive protein levels ( 30388399) Urate levels ( 31578528)
Interacting Genes		20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1	8 interacting genes: CDC23 DHPS HIF1A NIF3L1 PTBP2 RAB30 REL SDCBP
Entrez ID		58155	56648
HPRD ID		12233	10426
Ensembl ID		ENSG00000117569	ENSG00000163577
Uniprot IDs		B4DSS8 B4DSU5 Q9UKA9	Q9GZV4
PDB IDs		2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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