PTBP2 and PCBP3

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PTBP2	PCBP3
Description		polypyrimidine tract binding protein 2	poly(rC) binding protein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Growth Cone Neuronal Cell Body	Nucleus Cytosol Extracellular Exosome
	Molecular Function	RNA Binding MRNA Binding	DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Double-stranded DNA Binding RNA Binding C-rich Single-stranded DNA Binding
	Biological Process	MRNA Splice Site Selection Regulation Of Translation Spinal Cord Development Cerebellum Development Negative Regulation Of RNA Splicing Regulation Of RNA Splicing Regulation Of Neural Precursor Cell Proliferation	Negative Regulation Of Transcription By RNA Polymerase II MRNA Metabolic Process
Pathways
Drugs
Diseases
GWAS		Anorexia nervosa ( 31308545) Autism spectrum disorder ( 30804558) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 28892062 25673413 20935630 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically inactive individuals ( 28448500) Chronotype ( 30696823) Headache ( 29397368) Hip circumference ( 25673412) Number of sexual partners ( 30643258) Reaction time ( 29844566) Regular attendance at a pub or social club ( 29970889) Schizophrenia ( 19571811 22688191) Smoking status (ever vs never smokers) ( 30643258) Trunk fat mass adjusted for trunk lean mass ( 30944420) Waist circumference ( 25673412)	Ankle injury ( 28957384) Diffusing capacity of carbon monoxide ( 30694715) Insulin resistance/response ( 21901158) Intraocular pressure ( 29617998) Macular thickness ( 30535121) Myopia ( 27182965) Spatial processing ( 31596458) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		20 interacting genes: CALCOCO2 EIF5A2 ELAVL1 GBP1 GOLGA2 HNRNPAB HNRNPC HNRNPD KHDRBS1 KHDRBS3 KHSRP MATR3 PCBP3 PKN2 PUF60 QKI RBM10 RBM4 SNRPA TOM1	2 interacting genes: PTBP1 PTBP2
Entrez ID		58155	54039
HPRD ID		12233	10534
Ensembl ID		ENSG00000117569	ENSG00000183570
Uniprot IDs		B4DSS8 B4DSU5 Q9UKA9	P57721
PDB IDs		2CQ1 2MJU 4CQ1
Enriched GO Terms of Interacting Partners?
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