TCAF1 and EFEMP2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		TCAF1	EFEMP2
Description		TRPM8 channel associated factor 1	EGF containing fibulin extracellular matrix protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	Protein Binding Ion Channel Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Anion Channel Activity Negative Regulation Of Cell Migration Positive Regulation Of Protein Targeting To Membrane Positive Regulation Of Anion Channel Activity	Elastic Fiber Assembly
Pathways			Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases			Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS			Acne (severe) ( 24927181) Birth weight ( 31043758)
Interacting Genes		14 interacting genes: COIL EFEMP2 IKZF3 MID2 NFYA SF3B4 SPRY2 TCF3 TFIP11 TRIP6 UBC ZNF24 ZNF263 ZNF592	52 interacting genes: AMMECR1 APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PRPF31 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638
Entrez ID		9747	30008
HPRD ID		13813	05221
Ensembl ID		ENSG00000198420	ENSG00000172638
Uniprot IDs		B4DST7 Q9Y4C2	A0A024R5G1 O95967 Q9H3D5
PDB IDs			2KL7
Enriched GO Terms of Interacting Partners?
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