PIGR and RAB3B

Number of citations of the paper that reports this interaction (PubMedID 11832247)
29

Data Source:
HPRD (in vitro, in vivo)

		PIGR	RAB3B
Description		polymeric immunoglobulin receptor	RAB3B, member RAS oncogene family
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GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Azurophil Granule Membrane Receptor Complex Extracellular Exosome	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Endomembrane System Secretory Granule Cytoplasmic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	Polymeric Immunoglobulin Receptor Activity	GTPase Activity Protein Binding GTP Binding GDP Binding GTP-dependent Protein Binding Myosin V Binding
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Retina Homeostasis Immunoglobulin Transcytosis In Epithelial Cells Mediated By Polymeric Immunoglobulin Receptor Epidermal Growth Factor Receptor Signaling Pathway Fc Receptor Signaling Pathway Receptor Clustering Neutrophil Degranulation	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Antigen Processing And Presentation Rab Protein Signal Transduction Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle
Pathways		Neutrophil degranulation	RAB geranylgeranylation
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Coronary atherosclerosis (increased number of diseased vessels) (traffic exposure interaction) ( 28355232) Inflammatory bowel disease ( 23128233) Metabolite levels ( 23823483) Precuneus cortex volume ( 31530798)
Interacting Genes		4 interacting genes: AP1M1 CCL5 CD79A RAB3B	13 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RIMS2 RPH3A RPH3AL SMAD1 SMAD4 TGFBR1
Entrez ID		5284	5865
HPRD ID		01436	01540
Ensembl ID		ENSG00000162896	ENSG00000169213
Uniprot IDs		P01833	P20337
PDB IDs		1XED 2OCW 3CHN 3CM9 5D4K	3DZ8
Enriched GO Terms of Interacting Partners?
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