CD72 and BLNK

Number of citations of the paper that reports this interaction (PubMedID 10820378)
5

Data Source:
HPRD (in vivo)

		CD72	BLNK
Description		CD72 molecule	B cell linker
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Cytoplasm Cytosol Plasma Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Transmembrane Signaling Receptor Activity Signaling Receptor Binding Protein Binding Carbohydrate Binding	Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity SH3/SH2 Adaptor Activity Protein Binding
	Biological Process	Cell Adhesion	Inflammatory Response Humoral Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction B Cell Differentiation Intracellular Signal Transduction
Pathways		Other semaphorin interactions	Regulation of signaling by CBL Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases			Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS		Blood protein levels ( 30072576) Electroencephalogram traits ( 25387704)
Interacting Genes		8 interacting genes: BLNK CD5 GRB2 LMNA LYN PTPN6 SEMA4D SYK	20 interacting genes: BTK CBL CBLB CD72 CD79A CMTM3 CRKL ERBB2 GRAP2 GRB2 ITK LCP2 MAP4K1 NCK1 PLCG1 PLCG2 PTPN6 SH3KBP1 SYK VAV1
Entrez ID		971	29760
HPRD ID		00118	05153
Ensembl ID		ENSG00000137101	ENSG00000095585
Uniprot IDs		P21854 Q5TLG3	Q2MD54 Q2MD59 Q8WV28
PDB IDs
Enriched GO Terms of Interacting Partners?
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