SEC24C and WIPF1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SEC24C	WIPF1
Description		SEC24 homolog C, COPII coat complex component	WAS/WASL interacting protein family member 1
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat	Ruffle Cytosol Actin Filament Actin Cytoskeleton Actin Cortical Patch Cytoplasmic Vesicle
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Actin Filament Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating Cargo Loading Into COPII-coated Vesicle	Actin Cortical Patch Assembly Endocytosis Actin Polymerization Or Depolymerization Regulation Of Cell Shape Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Actin Nucleation Actin Cortical Patch Localization Response To Other Organism Protein-containing Complex Assembly
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC	Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)	Atrial fibrillation ( 30061737 29892015) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1	22 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70
Entrez ID		9632	7456
HPRD ID		06217	03835
Ensembl ID		ENSG00000176986	ENSG00000115935
Uniprot IDs		A0A024QZM6 P53992	A0A140VJZ9 O43516 Q2YDC4
PDB IDs		3EH2	2A41
Enriched GO Terms of Interacting Partners?
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