WIPF1 and HOMER3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		WIPF1	HOMER3
Description		WAS/WASL interacting protein family member 1	homer scaffold protein 3
Image
GO Annotations	Cellular Component	Ruffle Cytosol Actin Filament Actin Cytoskeleton Actin Cortical Patch Cytoplasmic Vesicle	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Neuron Projection
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Actin Filament Binding	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding
	Biological Process	Actin Cortical Patch Assembly Endocytosis Actin Polymerization Or Depolymerization Regulation Of Cell Shape Actin Filament-based Movement Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Actin Nucleation Actin Cortical Patch Localization Response To Other Organism Protein-containing Complex Assembly	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry
Pathways		Regulation of actin dynamics for phagocytic cup formation Regulation of actin dynamics for phagocytic cup formation RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate WASPs and WAVEs FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	Neurexins and neuroligins Neurexins and neuroligins
Drugs
Diseases
GWAS		Atrial fibrillation ( 30061737 29892015) Pulse pressure ( 27841878) Resting heart rate ( 27798624) Systolic blood pressure ( 27841878) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		22 interacting genes: ABI2 ACTC1 ACTG1 ALAS1 APBB1 CDC42 CRKL CTTN FASTK GRB2 HCK HOMER3 ITSN2 NCK1 PRKCQ PRPF40A SEC24C WAS WASL WBP4 WWP2 ZAP70	31 interacting genes: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EFHC1 EIF3D FAT1 FRYL GDF15 GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PRCC PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1
Entrez ID		7456	9454
HPRD ID		03835	07270
Ensembl ID		ENSG00000115935	ENSG00000051128
Uniprot IDs		A0A140VJZ9 O43516 Q2YDC4	Q9NSC5
PDB IDs		2A41	2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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