SEC24C and MOS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SEC24C	MOS
Description		SEC24 homolog C, COPII coat complex component	MOS proto-oncogene, serine/threonine kinase
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat	Cell Cytoplasm Cytosol
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Protein Serine/threonine Kinase Activity MAP Kinase Kinase Kinase Activity Protein Binding ATP Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating Cargo Loading Into COPII-coated Vesicle	MAPK Cascade Activation Of MAPKK Activity Activation Of MAPK Activity Meiotic Spindle Organization Chromatin Organization Positive Regulation Of MAPK Cascade Protein Autophosphorylation Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)	Height ( 18391951)
Interacting Genes		9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1	29 interacting genes: ACTN2 ATRIP BMPR2 BORCS6 CALCOCO2 CBY2 CCDC102B CCDC136 CCDC33 CCNDBP1 DYDC1 GFAP GOLGA2 HOMER3 HSPA1A KIFC3 KRT13 KRT15 KRT40 LZTS2 MID2 MTMR9 MYOD1 RHOU SEC24C SSX2IP TRAF1 TRIM27 USHBP1
Entrez ID		9632	4342
HPRD ID		06217	01816
Ensembl ID		ENSG00000176986	ENSG00000172680
Uniprot IDs		A0A024QZM6 P53992	P00540
PDB IDs		3EH2
Enriched GO Terms of Interacting Partners?
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