SEC24C and SEC23B

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		SEC24C	SEC23B
Description		SEC24 homolog C, COPII coat complex component	SEC23 homolog B, COPII coat complex component
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Endomembrane System COPII Vesicle Coat Perinuclear Region Of Cytoplasm Endoplasmic Reticulum Exit Site
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	GTPase Activator Activity Protein Binding Zinc Ion Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating Cargo Loading Into COPII-coated Vesicle	Intracellular Protein Transport Positive Regulation Of GTPase Activity Cargo Loading Into COPII-coated Vesicle
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases			Congenital dyserythropoietic anemias (CDAs)
GWAS		Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Crohn's disease ( 28067908) Self-rated health ( 27864402)
Interacting Genes		9 interacting genes: APP FBXO7 MIA2 MIA3 MOS SEC23A SEC23B SPP1 WIPF1	21 interacting genes: CPSF7 DTX2 FATE1 FBXW5 GALNT1 HOXA3 KDELR1 MAN2A1 NINL PRRC1 SEC24C SEC24D SKP1 SRPK1 SRPK2 SYNE4 TMED1 TMED10 TMED2 TMED9 UGT1A1
Entrez ID		9632	10483
HPRD ID		06217	11543
Ensembl ID		ENSG00000176986	ENSG00000101310
Uniprot IDs		A0A024QZM6 P53992	A0A2R8YFH5 Q15437
PDB IDs		3EH2
Enriched GO Terms of Interacting Partners?
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