MACROH2A1 and ATXN1L

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)

		MACROH2A1	ATXN1L
Description		macroH2A.1 histone	ataxin 1 like
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromosome, Telomeric Region Nucleosome Nuclear Chromatin Condensed Chromosome Sex Chromatin Barr Body Nucleus Nucleoplasm Pericentric Heterochromatin Nucleolus Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Dendrite
	Molecular Function	RDNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding Double-stranded Methylated DNA Binding Enzyme Binding Protein Kinase Binding Protein Serine/threonine Kinase Inhibitor Activity Chromatin DNA Binding Nucleosomal DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Promoter-specific Chromatin Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Nucleosome Assembly Chromatin Silencing Dosage Compensation Regulation Of Lipid Metabolic Process Negative Regulation Of Histone Phosphorylation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Gene Expression, Epigenetic Positive Regulation Of Keratinocyte Differentiation Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K4 Methylation Negative Regulation Of Histone H3-K27 Methylation Regulation Of Chromatin Silencing At RDNA Establishment Of Protein Localization To Chromatin Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Negative Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Response To Oxidative Stress Negative Regulation Of Protein Localization To Chromosome, Telomeric Region	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Brain Development Learning Memory Extracellular Matrix Organization Social Behavior Lung Alveolus Development Anatomical Structure Development Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways
Drugs
Diseases
GWAS			Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
Interacting Genes		9 interacting genes: APP ATF2 ATXN1L BARD1 BRCA1 ERICH2 PARP1 SPOP SRPK1	57 interacting genes: ACO2 ACOT7 ADORA1 AFAP1L2 ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ATXN1 CAMSAP2 CBFA2T2 CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FUS GAS7 GMEB2 GORASP2 GPATCH8 HGS HIVEP1 HSFX1 MACROH2A1 MATN2 MBD1 MBD6 MEOX2 METTL17 NBR1 NCOR1 NCOR2 NIT1 PHPT1 PICK1 PRRC2B RAD54L2 RBFOX2 RRAGC SCAF11 SMARCC2 SREBF1 ST6GALNAC6 STAC2 SUGP2 THY1 TMEM25 TMEM8B TRIP11 YY1AP1 ZC3H7B ZSWIM8
Entrez ID		9555	342371
HPRD ID		13624	19555
Ensembl ID		ENSG00000113648	ENSG00000224470
Uniprot IDs		O75367	P0C7T5
PDB IDs		1U35 1ZR3 1ZR5 2F8N 2FXK 3HQH 3HSV 3IID 3IIF 3IVB 5IIT 5LNC
Enriched GO Terms of Interacting Partners?
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