ATXN1L and CHD6

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)

		ATXN1L	CHD6
Description		ataxin 1 like	chromodomain helicase DNA binding protein 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Dendrite	Nucleoplasm
	Molecular Function	DNA Binding RNA Binding Protein Binding	Transcription Cofactor Binding DNA Binding DNA Helicase Activity ATP Binding DNA-dependent ATPase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Brain Development Learning Memory Extracellular Matrix Organization Social Behavior Lung Alveolus Development Anatomical Structure Development Positive Regulation Of Hematopoietic Stem Cell Proliferation	Chromatin Organization Viral Process DNA Duplex Unwinding Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Pathways
Drugs
Diseases
GWAS		Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)	Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Diastolic blood pressure ( 27841878) Gastric adenocarcinoma (histologically verified) ( 26098866) Hippocampal atrophy ( 22745009) Male-pattern baldness ( 28196072) Metabolite levels ( 23823483) Refractive astigmatism ( 30306274) Systolic blood pressure ( 27841878) Total cholesterol levels ( 30275531) Verbal declarative memory ( 25648963) Waist circumference ( 31170924)
Interacting Genes		57 interacting genes: ACO2 ACOT7 ADORA1 AFAP1L2 ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ATXN1 CAMSAP2 CBFA2T2 CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FUS GAS7 GMEB2 GORASP2 GPATCH8 HGS HIVEP1 HSFX1 MACROH2A1 MATN2 MBD1 MBD6 MEOX2 METTL17 NBR1 NCOR1 NCOR2 NIT1 PHPT1 PICK1 PRRC2B RAD54L2 RBFOX2 RRAGC SCAF11 SMARCC2 SREBF1 ST6GALNAC6 STAC2 SUGP2 THY1 TMEM25 TMEM8B TRIP11 YY1AP1 ZC3H7B ZSWIM8	6 interacting genes: ARAF ATXN1L H3-4 NFE2L2 TOLLIP ZFYVE9
Entrez ID		342371	84181
HPRD ID		19555	13049
Ensembl ID		ENSG00000224470	ENSG00000124177
Uniprot IDs		P0C7T5	Q8TD26
PDB IDs			2EPB
Enriched GO Terms of Interacting Partners?
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