ATXN1L and SMARCC2

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)

		ATXN1L	SMARCC2
Description		ataxin 1 like	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Dendrite	Nuclear Chromatin Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	DNA Binding RNA Binding Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding Histone Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Brain Development Learning Memory Extracellular Matrix Organization Social Behavior Lung Alveolus Development Anatomical Structure Development Positive Regulation Of Hematopoietic Stem Cell Proliferation	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated
Pathways			RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)	Asthma ( 31619474)
Interacting Genes		57 interacting genes: ACO2 ACOT7 ADORA1 AFAP1L2 ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ATXN1 CAMSAP2 CBFA2T2 CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FUS GAS7 GMEB2 GORASP2 GPATCH8 HGS HIVEP1 HSFX1 MACROH2A1 MATN2 MBD1 MBD6 MEOX2 METTL17 NBR1 NCOR1 NCOR2 NIT1 PHPT1 PICK1 PRRC2B RAD54L2 RBFOX2 RRAGC SCAF11 SMARCC2 SREBF1 ST6GALNAC6 STAC2 SUGP2 THY1 TMEM25 TMEM8B TRIP11 YY1AP1 ZC3H7B ZSWIM8	25 interacting genes: ARF6 ARRB2 ATXN1 ATXN1L BAZ1B CSNK2A1 EWSR1 FUS GATA1 IFTAP ITCH ITSN1 KLF1 MCPH1 NOVA1 PEX14 PHYHIP POLR2C RAB1B RELB SP1 SRGAP3 TAF15 TERF1 TERF2IP
Entrez ID		342371	6601
HPRD ID		19555	03437
Ensembl ID		ENSG00000224470	ENSG00000139613
Uniprot IDs		P0C7T5	A0A024RB22 F8VXC8 Q8TAQ2
PDB IDs
Enriched GO Terms of Interacting Partners?
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