MACROH2A1 and ERICH2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MACROH2A1	ERICH2
Description		macroH2A.1 histone	glutamate rich 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome Nuclear Chromosome, Telomeric Region Nucleosome Nuclear Chromatin Condensed Chromosome Sex Chromatin Barr Body Nucleus Nucleoplasm Pericentric Heterochromatin Nucleolus Extracellular Exosome
	Molecular Function	RDNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA Binding Protein Binding Double-stranded Methylated DNA Binding Enzyme Binding Protein Kinase Binding Protein Serine/threonine Kinase Inhibitor Activity Chromatin DNA Binding Nucleosomal DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Promoter-specific Chromatin Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization Nucleosome Assembly Chromatin Silencing Dosage Compensation Regulation Of Lipid Metabolic Process Negative Regulation Of Histone Phosphorylation Positive Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion Regulation Of Gene Expression, Epigenetic Positive Regulation Of Keratinocyte Differentiation Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K4 Methylation Negative Regulation Of Histone H3-K27 Methylation Regulation Of Chromatin Silencing At RDNA Establishment Of Protein Localization To Chromatin Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I Negative Regulation Of Cell Cycle G2/M Phase Transition Regulation Of Response To Oxidative Stress Negative Regulation Of Protein Localization To Chromosome, Telomeric Region
Pathways
Drugs
Diseases
GWAS			Metabolic syndrome ( 31589552)
Interacting Genes		9 interacting genes: APP ATF2 ATXN1L BARD1 BRCA1 ERICH2 PARP1 SPOP SRPK1	4 interacting genes: FBXO7 IWS1 MACROH2A1 SDCBP
Entrez ID		9555	285141
HPRD ID		13624
Ensembl ID		ENSG00000113648	ENSG00000204334
Uniprot IDs		O75367	A1L162
PDB IDs		1U35 1ZR3 1ZR5 2F8N 2FXK 3HQH 3HSV 3IID 3IIF 3IVB 5IIT 5LNC
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?