LONRF1 and TRIM9

Number of citations of the paper that reports this interaction (PubMedID 22493164)
5

Data Source:
BioGRID (two hybrid)

		LONRF1	TRIM9
Description		LON peptidase N-terminal domain and ring finger 1	tripartite motif containing 9
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Cytoplasm Cytoskeleton Synaptic Vesicle Cell Junction Dendrite Presynaptic Cytosol
	Molecular Function	Protein Binding Metal Ion Binding	SNARE Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Protein Polyubiquitination	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Colorectal cancer (diet interaction) ( 24743840)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Psychosis (atypical) ( 24132900) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Urate levels (BMI interaction) ( 25811787)
Interacting Genes		33 interacting genes: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CRX EFHC2 GORASP1 GORASP2 HSPB1 IHO1 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 NTAQ1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 XIAP	28 interacting genes: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 VASP
Entrez ID		91694	114088
HPRD ID		08674	05947
Ensembl ID		ENSG00000154359	ENSG00000100505
Uniprot IDs		Q17RB8	Q9C026
PDB IDs			2DB8
Enriched GO Terms of Interacting Partners?
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