LONRF1 and BYSL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LONRF1	BYSL
Description		LON peptidase N-terminal domain and ring finger 1	bystin like
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Preribosome, Small Subunit Precursor Intracellular Membrane-bounded Organelle Apical Part Of Cell
	Molecular Function	Protein Binding Metal Ion Binding	RNA Binding Protein Binding SnoRNA Binding
	Biological Process	Protein Polyubiquitination	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Trophectodermal Cell Differentiation RRNA Processing Cell Proliferation Ribosome Biogenesis Regulation Of Protein Localization To Nucleolus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS		Colorectal cancer (diet interaction) ( 24743840)	Hematological parameters ( 19820697) Mean corpuscular hemoglobin ( 20139978 19862010) Mean corpuscular volume ( 23263863 20139978 19862010) Menarche (age at onset) ( 27182965 25231870) Metabolite levels ( 23823483) Red blood cell count ( 20139978)
Interacting Genes		33 interacting genes: ADAMTSL4 ALAS1 ATG9A BRCA1 BYSL CALCOCO2 CRX EFHC2 GORASP1 GORASP2 HSPB1 IHO1 IKZF2 IQCF2 KAT5 KCTD9 KRT31 KRTAP13-1 LHX4 NR4A1 NTAQ1 PLSCR1 RBPMS SFN SPRY2 STAU1 STX11 TRIM42 TRIM9 UBE2L6 UCHL3 USP2 XIAP	67 interacting genes: AIMP2 APP BEND7 C1orf94 CCDC102B CCDC136 CCDC33 CDC23 CDCA7L CEP44 CEP57L1 CEP70 COIL DDX17 DOCK8 DVL2 EMD EPS8 FAM9B FXR2 GMCL1 GOLGA2 HMBOX1 IKZF1 KRT31 KRT40 KRT8 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP4-2 L3MBTL3 LMNA LONRF1 LTV1 LZTS2 MID1 MID2 MIPOL1 MRFAP1L1 MTUS2 NECAB2 OLIG3 PDE4DIP PHC2 PNMA1 PNMA2 RALYL SMN2 SSX2IP STX11 TEKT1 THAP1 TLE5 TNIP1 TRAF4 TRIM27 TRIM37 TRIM54 TRIP6 TRO TROAP UBE2H VPS37B ZBTB14 ZBTB8A ZFP64
Entrez ID		91694	705
HPRD ID		08674	04848
Ensembl ID		ENSG00000154359	ENSG00000112578
Uniprot IDs		Q17RB8	Q13895
PDB IDs			6G18 6G4S 6G4W
Enriched GO Terms of Interacting Partners?
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