TRIM9 and AP3M1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM9	AP3M1
Description		tripartite motif containing 9	adaptor related protein complex 3 subunit mu 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Synaptic Vesicle Cell Junction Dendrite Presynaptic Cytosol	Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane Axon Cytoplasm
	Molecular Function	SNARE Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Protein Domain Specific Binding Protein Homodimerization Activity	Protein Binding Rab GTPase Binding
	Biological Process	Synaptic Vesicle Exocytosis Protein Ubiquitination Negative Regulation Of SNARE Complex Assembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Calcium Ion-dependent Exocytosis	Protein Targeting To Lysosome Anterograde Axonal Transport Viral Process Vesicle-mediated Transport Anterograde Synaptic Vesicle Transport
Pathways		Antigen processing: Ubiquitination & Proteasome degradation	Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Psychosis (atypical) ( 24132900) Response to cyclophosphamide in systemic lupus erythematosus with lupus nephritis ( 26980576) Urate levels (BMI interaction) ( 25811787)	Cardiac troponin-I levels ( 31014085) Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Interacting Genes		28 interacting genes: AP3M1 BTRC CHFR CSNK1D CWF19L2 DTNBP1 DTX3L EVL EXOC1 GFM2 LONRF1 MDM2 MNAT1 MUL1 NCF1 NFKBID PCGF3 RNF166 RPL4P5 SNAP25 SPG21 TRIM27 TRIM46 TRIM8 TSSK3 USP2 USP21 VASP	8 interacting genes: AGTRAP AQP4 CRMP1 RUFY1 SIPA1L2 TGOLN2 TRIM14 TRIM9
Entrez ID		114088	26985
HPRD ID		05947	16496
Ensembl ID		ENSG00000100505	ENSG00000185009
Uniprot IDs		Q9C026	A0A024QZR5 B4DRN6 Q9Y2T2
PDB IDs		2DB8
Enriched GO Terms of Interacting Partners?
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