PRPF3 and GTPBP3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRPF3	GTPBP3
Description		pre-mRNA processing factor 3	GTP binding protein 3, mitochondrial
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Cytoplasm Mitochondrion
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	GTPase Activity Protein Binding GTP Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	TRNA Wobble Uridine Modification TRNA Methylation Embryonic Organ Development
Pathways		mRNA Splicing - Major Pathway	tRNA modification in the mitochondrion
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Blood protein levels ( 28240269) Chronotype ( 27494321) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 27863252) Plateletcrit ( 27863252)	Mitochondrial DNA copy number ( 30704525)
Interacting Genes		31 interacting genes: BRCA1 CASK CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GPRASP2 GTPBP3 MAPRE1 MID2 NAV2 NKAP PCBP1 PHC2 PRPF31 PSMD3 RBM39 SART3 SNIP1 SNRNP200 TRIM39 U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZGPAT	9 interacting genes: CIC DCAF8 GNE PARP11 PFKL PRPF3 PTAFR RIBC2 SINHCAF
Entrez ID		9129	84705
HPRD ID		07389	12255
Ensembl ID		ENSG00000117360	ENSG00000130299
Uniprot IDs		O43395	B7Z563 Q969Y2
PDB IDs		1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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