PRPF3 and DPY30

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRPF3	DPY30
Description		pre-mRNA processing factor 3	dpy-30 histone methyltransferase complex regulatory subunit
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	Endosomal Transport Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation
Pathways		mRNA Splicing - Major Pathway	PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Blood protein levels ( 28240269) Chronotype ( 27494321) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 27863252) Plateletcrit ( 27863252)	Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)
Interacting Genes		31 interacting genes: BRCA1 CASK CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GPRASP2 GTPBP3 MAPRE1 MID2 NAV2 NKAP PCBP1 PHC2 PRPF31 PSMD3 RBM39 SART3 SNIP1 SNRNP200 TRIM39 U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZGPAT	14 interacting genes: ARFGEF1 ASH2L CHMP2B DYDC1 GTF2I H3-4 KMT2C OTX1 PRPF3 PRRC2B PSMD14 SETD1A TMCC2 UBC
Entrez ID		9129	84661
HPRD ID		07389	17434
Ensembl ID		ENSG00000117360	ENSG00000162961
Uniprot IDs		O43395	B4DIS3 Q9C005
PDB IDs		1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	3G36 4RIQ 4RT4 4RTA 6E2H
Enriched GO Terms of Interacting Partners?
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