PRPF3 and PCBP1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid, two hybrid)

		PRPF3	PCBP1
Description		pre-mRNA processing factor 3	poly(rC) binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding
	Biological Process	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases		Retinitis pigmentosa (RP)
GWAS		Blood protein levels ( 28240269) Chronotype ( 27494321) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 27863252) Plateletcrit ( 27863252)	Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		31 interacting genes: BRCA1 CASK CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GPRASP2 GTPBP3 MAPRE1 MID2 NAV2 NKAP PCBP1 PHC2 PRPF31 PSMD3 RBM39 SART3 SNIP1 SNRNP200 TRIM39 U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZGPAT	42 interacting genes: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 MOGS NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM42 SNRPA SRPK2 SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830
Entrez ID		9129	5093
HPRD ID		07389	03128
Ensembl ID		ENSG00000117360	ENSG00000169564
Uniprot IDs		O43395	Q15365 Q53SS8
PDB IDs		1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9	1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?
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