GTPBP3 and PRPF3

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GTPBP3	PRPF3
Description		GTP binding protein 3, mitochondrial	pre-mRNA processing factor 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Nucleus Nucleoplasm Spliceosomal Complex Cytosol Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding	RNA Binding Protein Binding Identical Protein Binding
	Biological Process	TRNA Wobble Uridine Modification TRNA Methylation Embryonic Organ Development	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways		tRNA modification in the mitochondrion	mRNA Splicing - Major Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Mitochondrial DNA copy number ( 30704525)	Blood protein levels ( 28240269) Chronotype ( 27494321) Low density lipoprotein cholesterol levels ( 30498476) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Platelet count ( 27863252) Plateletcrit ( 27863252)
Interacting Genes		9 interacting genes: CIC DCAF8 GNE PARP11 PFKL PRPF3 PTAFR RIBC2 SINHCAF	31 interacting genes: BRCA1 CASK CCDC85B CDC5L CTNNBL1 DPY30 DVL2 DVL3 FAM9B FRA10AC1 GPRASP2 GTPBP3 MAPRE1 MID2 NAV2 NKAP PCBP1 PHC2 PRPF31 PSMD3 RBM39 SART3 SNIP1 SNRNP200 TRIM39 U2AF2 USP4 WBP4 ZBTB8A ZCCHC10 ZGPAT
Entrez ID		84705	9129
HPRD ID		12255	07389
Ensembl ID		ENSG00000130299	ENSG00000117360
Uniprot IDs		B7Z563 Q969Y2	O43395
PDB IDs			1X4Q 3JCR 5O9Z 6AH0 6AHD 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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