DPY30 and SETD1A

Number of citations of the paper that reports this interaction (PubMedID 23870121)
65

Data Source:
BioGRID (pull down, affinity chromatography technology)

		DPY30	SETD1A
Description		dpy-30 histone methyltransferase complex regulatory subunit	SET domain containing 1A, histone lysine methyltransferase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Golgi Apparatus Trans-Golgi Network Histone Methyltransferase Complex MLL3/4 Complex Set1C/COMPASS Complex	Nuclear Chromatin Nucleus Nucleoplasm Nuclear Speck Histone Methyltransferase Complex Set1C/COMPASS Complex
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	RNA Binding Protein Binding Beta-catenin Binding Transcription Factor Binding Histone Methyltransferase Activity (H3-K4 Specific)
	Biological Process	Endosomal Transport Regulation Of Megakaryocyte Differentiation Histone H3-K4 Methylation	Histone H3-K4 Dimethylation Regulation Of Megakaryocyte Differentiation Histone H3-K4 Trimethylation Histone H3-K4 Monomethylation Regulation Of Hematopoietic Stem Cell Differentiation Regulation Of Chromatin Organization
Pathways		PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function	PKMTs methylate histone lysines RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS		Inflammatory biomarkers ( 24182552) Interleukin-18 levels ( 31584380) Male-pattern baldness ( 28196072)	Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Mean corpuscular hemoglobin ( 27863252) Multiple sclerosis ( 31604244) Parkinson's disease ( 31660654) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		14 interacting genes: ARFGEF1 ASH2L CHMP2B DYDC1 GTF2I H3-4 KMT2C OTX1 PRPF3 PRRC2B PSMD14 SETD1A TMCC2 UBC	6 interacting genes: BCKDK DPY30 EP300 H3C1 H3C14 LBP
Entrez ID		84661	9739
HPRD ID		17434	13795
Ensembl ID		ENSG00000162961	ENSG00000099381
Uniprot IDs		B4DIS3 Q9C005	O15047
PDB IDs		3G36 4RIQ 4RT4 4RTA 6E2H	3S8S 3UVN 4EWR
Enriched GO Terms of Interacting Partners?
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