SH2D2A and ZYG11B

		SH2D2A	ZYG11B
Description		SH2 domain containing 2A	zyg-11 family member B, cell cycle regulator
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Cul2-RING Ubiquitin Ligase Complex
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Signaling Adaptor Activity
	Biological Process	Angiogenesis Signal Transduction Cell Proliferation Positive Regulation Of Signal Transduction Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Platelet count ( 27863252) SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		29 interacting genes: APPL1 ARID5A CRK DAPK1 EGFR ERBB2 ITK KDR LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1 ZYG11B	13 interacting genes: ARPC2 ASPA BTBD2 BTF3L4 CFL2 CUL2 ELOB ELOC NDC1 OSBPL9 SH2D2A TLR6 UCK2
Entrez ID		9047	79699
HPRD ID		05152	13356
Ensembl ID		ENSG00000027869	ENSG00000162378
Uniprot IDs		Q5UBZ2 Q5UBZ3 Q9NP31	A8DPD7 B4DK95 Q9C0D3
PDB IDs
Enriched GO Terms of Interacting Partners?
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