SH2D2A and PPP1R21

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

		SH2D2A	PPP1R21
Description		SH2 domain containing 2A	protein phosphatase 1 regulatory subunit 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Early Endosome Membrane
	Molecular Function	SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding Signaling Adaptor Activity
	Biological Process	Angiogenesis Signal Transduction Cell Proliferation Positive Regulation Of Signal Transduction Cell Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway
Pathways		VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS		Platelet count ( 27863252) SjÃ¶gren's syndrome ( 28076899)	Chronotype ( 30696823) Colorectal cancer ( 30529582) Educational attainment ( 27046643) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Joint mobility (Beighton score) ( 27182965) Mean corpuscular hemoglobin concentration ( 29403010) Prudent dietary pattern ( 28644415) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		29 interacting genes: APPL1 ARID5A CRK DAPK1 EGFR ERBB2 ITK KDR LCK LINC02875 LNX1 LRRFIP1 LRRK1 MAP3K2 MAPK7 MFHAS1 NAA16 PLCG1 PPP1R21 SOCS3 SPTB STAT3 SYK TSC1 TXK VCP ZHX3 ZSCAN1 ZYG11B	6 interacting genes: FBXO7 MTNR1B RTN4 SH2D2A SH3GL2 ZDHHC17
Entrez ID		9047	129285
HPRD ID		05152	17294
Ensembl ID		ENSG00000027869	ENSG00000162869
Uniprot IDs		Q5UBZ2 Q5UBZ3 Q9NP31	Q6ZMI0
PDB IDs
Enriched GO Terms of Interacting Partners?
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