BAZ1B and SMARCE1

Number of citations of the paper that reports this interaction (PubMedID 12837248)
65

Data Source:
HPRD (in vivo, in vitro)

		BAZ1B	SMARCE1
Description		bromodomain adjacent to zinc finger domain 1B	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Image			No pdb structure
GO Annotations	Cellular Component	Condensed Chromosome Nucleoplasm Pericentric Heterochromatin Nuclear Body Nuclear Replication Fork	Nuclear Chromosome Nuclear Chromatin Nucleus Nucleoplasm SWI/SNF Complex Protein-containing Complex NpBAF Complex NBAF Complex
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Zinc Ion Binding Histone Kinase Activity Histone Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Chromatin Binding Transcription Coactivator Activity RNA Binding Protein Binding N-acetyltransferase Activity Nuclear Receptor Binding Nucleosomal DNA Binding Protein N-terminus Binding
	Biological Process	Chromatin Assembly Or Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Histone Phosphorylation Peptidyl-tyrosine Phosphorylation Positive Regulation Of Gene Expression, Epigenetic	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Neurogenesis ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Nucleic Acid-templated Transcription
Pathways		B-WICH complex positively regulates rRNA expression Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		C-reactive protein levels or HDL-cholesterol levels (pleiotropy) ( 27286809) Hypertriglyceridemia ( 23505323) Hyperuricemia ( 29124443) Metabolic syndrome ( 31589552) Migraine ( 27182965) Protein C levels ( 20802025) Pursuit maintenance gain ( 29064472) Serum uric acid levels ( 30993211) Triglycerides ( 20864672) Urate levels ( 23263486) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 28448500)	Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 31361310) Asthma ( 30929738 31619474) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eczema ( 31361310)
Interacting Genes		10 interacting genes: CDT1 MTNR1A MYO1C NR4A2 PCNA SMARCA1 SMARCA5 SMARCC2 SMARCE1 SUMO2	64 interacting genes: AMOTL2 AR ARID2 BAZ1B BRAP BRMS1 CCDC136 CCDC172 CDR2 CEP170P1 CEP63 CEP70 DISC1 EPS8 ESR1 ESR2 EXOC7 GATA1 GOLGA2 ING5 ITCH JAKMIP2 KIFC3 KLF1 KRT15 KRT31 KRT40 KRTAP10-9 MDM2 MED4 MEOX2 MIPOL1 MRFAP1L1 MTUS2 NBPF22P NCOA1 NCOA2 NCOA3 NOTCH2NLA NR0B2 NR3C1 NUP62 PGR PRMT5 RALBP1 RARB RCOR1 RELB RINT1 SIN3A SIN3B SMAD1 SMARCA4 SPAG5 SRC STX11 SYCE1 TFE3 TFIP11 TNIK TRIM54 TRIP10 TXLNA USHBP1
Entrez ID		9031	6605
HPRD ID		10416	04382
Ensembl ID		ENSG00000009954	ENSG00000073584
Uniprot IDs		Q9UIG0	A0A024R1S7 Q969G3
PDB IDs		1F62 5NNF
Enriched GO Terms of Interacting Partners?
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