NR1I2 and UBR5

  • Number of citations of the paper that reports this interaction (PubMedID 24438055)
  • 12
  • Data Source:
  • BioGRID (enzymatic study)

NR1I2

UBR5

Description nuclear receptor subfamily 1 group I member 2 ubiquitin protein ligase E3 component n-recognin 5
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Total cholesterol levels ( 30275531)
  • Chromosomal aberration frequency (total) ( 31586183)
  • Rate of cognitive decline in mild cognitive impairment (time interaction) ( 22833209)
  • Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes 32 interacting genes: ACTN2 ATP6AP1 CHMP1A DNMT3L DYRK2 EP300 FGR HNF4A MAPK7 NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NFATC4 NR0B2 NR5A2 NUCB2 POU1F1 PPARGC1A PSMC5 RBCK1 RPS6KB1 RXRA RXRB RXRG SDF4 SRC TADA3 TFAP2C UBE2I UBR5 31 interacting genes: BARD1 BUB3 CIB1 CSPP1 DYRK2 ERG GSK3B KPNA1 KPNA2 KPNB1 MAPK1 MOAP1 NR1I2 OTUD5 PAIP1 PAIP2 PCK1 PGR SATB1 SMAD2 SOX2 TCEA1 TOPBP1 TXNIP UBC UBE2A UBE2B UBE2D2 UBE2D3 UBE2L3 ZNF207
Entrez ID 8856 51366
HPRD ID 04346 06436
Ensembl ID ENSG00000144852 ENSG00000104517
Uniprot IDs F1D8P9 O75469 O95071
PDB IDs 1ILG 1ILH 1M13 1NRL 1SKX 2O9I 2QNV 3CTB 3HVL 3R8D 4J5W 4J5X 4NY9 4S0S 4S0T 4X1F 4X1G 4XAO 4XHD 5A86 5X0R 6BNS 6DUP 6S41 1I2T 2QHO 3PT3
Enriched GO Terms of Interacting Partners?
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