NR1I2 and CHMP1A

Number of citations of the paper that reports this interaction (PubMedID 15604093)
54

Data Source:
BioGRID (two hybrid)

		NR1I2	CHMP1A
Description		nuclear receptor subfamily 1 group I member 2	charged multivesicular body protein 1A
Image
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nuclear Body Intermediate Filament Cytoskeleton RNA Polymerase II Transcription Factor Complex	Condensed Nuclear Chromosome ESCRT III Complex Cell Early Endosome Multivesicular Body Microtubule Organizing Center Endomembrane System Nuclear Matrix Extracellular Exosome
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Steroid Hormone Receptor Activity Transcription Coactivator Activity Nuclear Receptor Activity Protein Binding Transcription Factor Binding Drug Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity Signaling Receptor Activity Transcription Factor Activity, Direct Ligand Regulated Sequence-specific DNA Binding	Protein Binding Metallopeptidase Activity Zinc Ion Binding Protein Domain Specific Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Lipid Metabolic Process Xenobiotic Metabolic Process Signal Transduction Multicellular Organism Development Steroid Metabolic Process Cell Differentiation Intracellular Receptor Signaling Pathway Response To Lipid Cholesterol Homeostasis Exogenous Drug Catabolic Process Xenobiotic Transport Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Lipid Homeostasis Cellular Response To Lipopolysaccharide	Proteolysis Nucleus Organization Mitotic Chromosome Condensation Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Vesicle-mediated Transport Gene Silencing Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Late Endosome To Vacuole Transport Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Cell Division Midbody Abscission Regulation Of Mitotic Spindle Assembly ESCRT III Complex Disassembly
Pathways			HCMV Late Events
Drugs		Vitamin E Oxiconazole Phenytoin Diethylstilbestrol Clotrimazole Pentobarbital Progesterone Spironolactone Lindane Flutamide Ritonavir Erlotinib Cyclophosphamide Mephenytoin Carbamazepine Tamoxifen Warfarin Ethotoin Estradiol Mifepristone Methylphenobarbital Ethinyl Estradiol Ketoconazole Fenofibrate Rifampicin Clonazepam Miconazole Nifedipine Econazole Sulfinpyrazone Phenobarbital Ifosfamide Rifaximin Paclitaxel Dexamethasone Docetaxel Bezafibrate Genistein Prasterone Hyperforin Resveratrol Pregnenolone Quercetin SR12813 Afimoxifene Phenolphthalein Permethrin Chenodeoxycholic acid N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE Hexestrol Triclosan Rilpivirine Pyrethrum extract Myrrh Piperine Troleandomycin
Diseases
GWAS		Hippocampal volume in Alzheimer's disease dementia ( 29274321) Total cholesterol levels ( 30275531)	Diastolic blood pressure ( 30578418) Estimated glomerular filtration rate ( 31152163) Low tan response ( 29739929) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Plasma homocysteine levels ( 30339177) Red vs. brown/black hair color ( 30531825)
Interacting Genes		32 interacting genes: ACTN2 ATP6AP1 CHMP1A DNMT3L DYRK2 EP300 FGR HNF4A MAPK7 NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NFATC4 NR0B2 NR5A2 NUCB2 POU1F1 PPARGC1A PSMC5 RBCK1 RPS6KB1 RXRA RXRB RXRG SDF4 SRC TADA3 TFAP2C UBE2I UBR5	9 interacting genes: CHMP1B LNPK NR1I2 STAMBP UBE2I USP8 VPS4A VPS4B ZDHHC17
Entrez ID		8856	5119
HPRD ID		04346	01237
Ensembl ID		ENSG00000144852	ENSG00000131165
Uniprot IDs		F1D8P9 O75469	Q9HD42
PDB IDs		1ILG 1ILH 1M13 1NRL 1SKX 2O9I 2QNV 3CTB 3HVL 3R8D 4J5W 4J5X 4NY9 4S0S 4S0T 4X1F 4X1G 4XAO 4XHD 5A86 5X0R 6BNS 6DUP 6S41	2JQ9 2YMB 4A5X
Enriched GO Terms of Interacting Partners?
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