STX11 and ZNF587

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		STX11	ZNF587
Description		syntaxin 11	zinc finger protein 587
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane	Nucleus
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion	Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases		Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587	43 interacting genes: ADAMTSL4 CARD9 CCDC136 CEP44 CEP70 CSRNP1 FSD2 GOLGA2 GOPC HMBOX1 KRT38 KRT40 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP2-4 KRTAP5-9 MDFI MEOX2 MID2 MTUS2 NOTCH2NLA PLSCR1 PNMA2 PRPF31 RUNDC3A SMAD9 SPRY2 SSX2IP STX11 TCF4 TMCC2 TNS2 TRAF1 TRIM36 TRIM41 TRIM54 TSGA10 ZBTB8A ZNF417
Entrez ID		8676	84914
HPRD ID		09231	15864
Ensembl ID		ENSG00000135604	ENSG00000198466
Uniprot IDs		O75558	Q96SQ5
PDB IDs
Enriched GO Terms of Interacting Partners?
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