STX11 and EIF1AD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		STX11	EIF1AD
Description		syntaxin 11	eukaryotic translation initiation factor 1A domain containing
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane	Nucleus
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Translation Initiation Factor Activity Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion	Translational Initiation
Pathways
Drugs
Diseases		Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)
Interacting Genes		64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587	12 interacting genes: BEND7 CEP55 DPPA2 GLYR1 MEOX2 SDCBP SDCBP2 STAT1 STX11 TBC1D5 ZBTB14 ZBTB8A
Entrez ID		8676	84285
HPRD ID		09231	14411
Ensembl ID		ENSG00000135604	ENSG00000175376
Uniprot IDs		O75558	A0A024R5B9 Q8N9N8
PDB IDs			2DGY
Enriched GO Terms of Interacting Partners?
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