STX11 and PPP1R18

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		STX11	PPP1R18
Description		syntaxin 11	protein phosphatase 1 regulatory subunit 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane	Cytoplasm Cytoskeleton
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding	Actin Binding Protein Binding Phosphatase Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways
Drugs
Diseases		Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730)
Interacting Genes		64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587	37 interacting genes: CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 DES FAM9B FSD2 GOLGA2 HOMER3 KASH5 KCTD9 KRT13 KRT15 KRT19 KRT31 KRT40 LZTS2 MID2 MTUS2 NEFL PDE4DIP PPP1CA PPP1CC SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM69 TSGA10 VPS52
Entrez ID		8676	170954
HPRD ID		09231	11172
Ensembl ID		ENSG00000135604	ENSG00000146112
Uniprot IDs		O75558	A0A024RCJ8 Q6NYC8
PDB IDs
Enriched GO Terms of Interacting Partners?
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