STX11 and TNFRSF21

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		STX11	TNFRSF21
Description		syntaxin 11	TNF receptor superfamily member 21
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Axon Intrinsic Component Of Plasma Membrane
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion	B Cell Apoptotic Process Adaptive Immune Response Apoptotic Process Humoral Immune Response Axonal Fasciculation Regulation Of Lipid Metabolic Process Negative Regulation Of B Cell Proliferation Negative Regulation Of Myelination Negative Regulation Of T Cell Proliferation Myelination Regulation Of Oligodendrocyte Differentiation T Cell Receptor Signaling Pathway Neuron Apoptotic Process Cellular Response To Tumor Necrosis Factor Oligodendrocyte Apoptotic Process Negative Regulation Of Interleukin-5 Secretion Negative Regulation Of Interleukin-13 Secretion Negative Regulation Of Interleukin-10 Secretion
Pathways			PPARA activates gene expression
Drugs
Diseases		Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Panic disorder ( 19165232) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122)
Interacting Genes		64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587	6 interacting genes: CLIP3 MATR3 NSD1 STX11 TRADD WASH2P
Entrez ID		8676	27242
HPRD ID		09231	05759
Ensembl ID		ENSG00000135604	ENSG00000146072
Uniprot IDs		O75558	A0A024RD71 O75509
PDB IDs			2DBH 3QO4 3U3P 3U3Q 3U3S 3U3T 3U3V
Enriched GO Terms of Interacting Partners?
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