EIF1AD and TBC1D5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EIF1AD	TBC1D5
Description		eukaryotic translation initiation factor 1A domain containing	TBC1 domain family member 5
Image
GO Annotations	Cellular Component	Nucleus	Autophagosome Golgi Apparatus Cytosol Endosome Membrane AP-2 Adaptor Complex Retromer Complex Intracellular Membrane-bounded Organelle Atg1/ULK1 Kinase Complex
	Molecular Function	Translation Initiation Factor Activity Protein Binding	GTPase Activator Activity Protein Binding Rab GTPase Binding AP-2 Adaptor Complex Binding Protein-containing Complex Binding Retromer Complex Binding
	Biological Process	Translational Initiation	Positive Regulation Of Receptor Internalization Intracellular Protein Transport Autophagy Macroautophagy Retrograde Transport, Endosome To Golgi Response To Starvation Activation Of GTPase Activity Regulation Of Cilium Assembly
Pathways
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	General risk tolerance (MTAG) ( 30643258) Height ( 28552196) Mean platelet volume ( 27863252) Midgestational circulating levels of PBDEs (fetal genetic effect) ( 28235828) Platelet count ( 27863252) Platelet distribution width ( 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656) Self-reported risk-taking behaviour ( 30271922)
Interacting Genes		12 interacting genes: BEND7 CEP55 DPPA2 GLYR1 MEOX2 SDCBP SDCBP2 STAT1 STX11 TBC1D5 ZBTB14 ZBTB8A	7 interacting genes: AP2M1 ATXN1 EIF1AD GABARAPL1 GABARAPL2 MAP1LC3A UBC
Entrez ID		84285	9779
HPRD ID		14411	10262
Ensembl ID		ENSG00000175376	ENSG00000131374
Uniprot IDs		A0A024R5B9 Q8N9N8	B9A6K1 Q92609
PDB IDs		2DGY	5GTU
Enriched GO Terms of Interacting Partners?
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