PPP1R18 and VPS52

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PPP1R18	VPS52
Description		protein phosphatase 1 regulatory subunit 18	VPS52 subunit of GARP complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton	GARP Complex Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome EARP Complex
	Molecular Function	Actin Binding Protein Binding Phosphatase Binding	Protein Binding Rab GTPase Binding Syntaxin Binding
	Biological Process		Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development
Pathways			Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) Lung cancer ( 28604730)	Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		37 interacting genes: CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 DES FAM9B FSD2 GOLGA2 HOMER3 KASH5 KCTD9 KRT13 KRT15 KRT19 KRT31 KRT40 LZTS2 MID2 MTUS2 NEFL PDE4DIP PPP1CA PPP1CC SPDL1 STX11 TCF4 TEX11 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54 TRIM69 TSGA10 VPS52	50 interacting genes: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EEF1AKNMT EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 HGS KANK2 KIAA1217 KIF5B KLC3 LMO4 MAGEL2 MAPK3 MFAP1 MRPL11 NFKBIB NOP2 PIMREG PPP1R18 PRKAA1 PRKAA2 RAB4A RABEP2 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS53 WTAP ZMAT2
Entrez ID		170954	6293
HPRD ID		11172	09142
Ensembl ID		ENSG00000146112	ENSG00000223501
Uniprot IDs		A0A024RCJ8 Q6NYC8	A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4
PDB IDs
Enriched GO Terms of Interacting Partners?
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