STK16 and EFEMP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		STK16	EFEMP2
Description		serine/threonine kinase 16	EGF containing fibulin extracellular matrix protein 2
Image
GO Annotations	Cellular Component	Cytoplasm Golgi-associated Vesicle Cytosol Membrane Perinuclear Region Of Cytoplasm	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Protein Serine/threonine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Peptidyl-tyrosine Phosphorylation Positive Regulation Of Transcription By RNA Polymerase II Protein Autophosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus	Elastic Fiber Assembly
Pathways			Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases			Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS			Acne (severe) ( 24927181) Birth weight ( 31043758)
Interacting Genes		47 interacting genes: ADAMTSL4 CALCOCO2 CCDC33 CRX CSNK2B DNAJA3 DRG1 EFEMP2 EFHC2 ELK1 FLACC1 IKZF3 INCA1 KCTD14 KCTD17 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP13-1 KRTAP26-1 MBP MEOX2 MGAT5B MIIP MTUS2 NAGK NIF3L1 NOTCH2NLA PCSK5 PLSCR1 PLSCR3 REL RFX6 RPIA SAXO1 SKIL SPRY2 TCF12 TCF4 TLE5 TNFAIP1 TRAF3IP2 TRIM27 TRIM42 TRIP6	52 interacting genes: AMMECR1 APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PRPF31 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638
Entrez ID		8576	30008
HPRD ID		05281	05221
Ensembl ID		ENSG00000115661	ENSG00000172638
Uniprot IDs		B4DPS1 B8ZZI5 O75716	A0A024R5G1 O95967 Q9H3D5
PDB IDs		2BUJ	2KL7
Enriched GO Terms of Interacting Partners?
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