DYRK2 and NR1I2

  • Number of citations of the paper that reports this interaction (PubMedID 24438055)
  • 12
  • Data Source:
  • BioGRID (affinity chromatography technology, enzymatic study)

DYRK2

NR1I2

Description dual specificity tyrosine phosphorylation regulated kinase 2 nuclear receptor subfamily 1 group I member 2
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Daytime sleep phenotypes ( 27126917)
  • Itch intensity from mosquito bite ( 28199695)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Metabolite levels ( 23823483)
  • Mosquito bite size ( 28199695)
  • Systemic lupus erythematosus ( 28714469)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
  • Total cholesterol levels ( 30275531)
Interacting Genes 22 interacting genes: APP ATM DYRK4 EIF2B5 H2BC21 H3-4 IKZF1 KATNA1 KXD1 LRRK2 LZTS2 MAPT MDM2 NR1I2 RAD54B SIAH2 SP100 TERT UBE2D1 UBR5 WDR62 ZBTB9 32 interacting genes: ACTN2 ATP6AP1 CHMP1A DNMT3L DYRK2 EP300 FGR HNF4A MAPK7 NCOA1 NCOA2 NCOA3 NCOA6 NCOR2 NFATC4 NR0B2 NR5A2 NUCB2 POU1F1 PPARGC1A PSMC5 RBCK1 RPS6KB1 RXRA RXRB RXRG SDF4 SRC TADA3 TFAP2C UBE2I UBR5
Entrez ID 8445 8856
HPRD ID 04606 04346
Ensembl ID ENSG00000127334 ENSG00000144852
Uniprot IDs Q92630 F1D8P9 O75469
PDB IDs 3K2L 3KVW 4AZF 5LXC 5LXD 5ZTN 6HDP 6HDR 6K0J 1ILG 1ILH 1M13 1NRL 1SKX 2O9I 2QNV 3CTB 3HVL 3R8D 4J5W 4J5X 4NY9 4S0S 4S0T 4X1F 4X1G 4XAO 4XHD 5A86 5X0R 6BNS 6DUP 6S41
Enriched GO Terms of Interacting Partners?
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