DYRK2 and IKZF1

  • Number of citations of the paper that reports this interaction (PubMedID 25416956)
  • 381
  • Data Source:
  • BioGRID (two hybrid)

DYRK2

IKZF1

Description dual specificity tyrosine phosphorylation regulated kinase 2 IKAROS family zinc finger 1
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (C9orf72 mutation interaction) ( 22959728)
  • Daytime sleep phenotypes ( 27126917)
  • Itch intensity from mosquito bite ( 28199695)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Metabolite levels ( 23823483)
  • Mosquito bite size ( 28199695)
  • Systemic lupus erythematosus ( 28714469)
Interacting Genes 22 interacting genes: APP ATM DYRK4 EIF2B5 H2BC21 H3-4 IKZF1 KATNA1 KXD1 LRRK2 LZTS2 MAPT MDM2 NR1I2 RAD54B SIAH2 SP100 TERT UBE2D1 UBR5 WDR62 ZBTB9 79 interacting genes: AEN ALKBH3 ANKRD11 AP1M1 AP2M1 ARMC7 BYSL C1orf109 C1orf174 C8orf33 CBX8 CDK2AP2 CEP57L1 CHD3 CKS1B CSNK1G1 CTBP1 DCX DDB1 DDX6 DYRK2 FAM161A FAM214B FAM50B FAM74A4 FGF12 FOXP1 FRMD6 GLRX3 GMCL2 GTF2B HDAC1 HDAC2 IKZF2 IKZF3 IKZF4 IKZF5 ISCU KIF9 LHX4 LMO3 LSM4 MAD2L2 MCRS1 MORF4L1 MORF4L2 MPPED2 NEK6 NME7 NOC4L NUDT21 PIN1 PNKP PRKAB2 PSMA1 PSMA4 RAD51D RBBP8 RNF6 RUNX1 RWDD2B SAP18 SCNM1 SDCBP SH2D4A SHFL SIN3A SIN3B SMARCA4 SNRPF SNW1 SPATC1L SYT17 TBP TDG UBE2I ZMAT2 ZNF417 ZNF581
Entrez ID 8445 10320
HPRD ID 04606 04318
Ensembl ID ENSG00000127334 ENSG00000185811
Uniprot IDs Q92630 A0A2R8Y4D3 C9JTB0 Q13422 R9R4D9
PDB IDs 3K2L 3KVW 4AZF 5LXC 5LXD 5ZTN 6HDP 6HDR 6K0J 6H0F
Enriched GO Terms of Interacting Partners?
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