ASCC2 and OLA1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	OLA1
Description		activating signal cointegrator 1 complex subunit 2	Obg like ATPase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Extracellular Region Nucleolus Cytoplasm Centrosome Cytosol Membrane Platelet Alpha Granule Lumen Extracellular Exosome
	Molecular Function	Ubiquitin Binding	Protein Binding ATP Binding GTP Binding ATPase Activity Ribosome Binding Ribosomal Large Subunit Binding Cadherin Binding Metal Ion Binding
	Biological Process	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated	Platelet Degranulation ATP Metabolic Process
Pathways		ALKBH3 mediated reversal of alkylation damage	Platelet degranulation
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Blood protein levels ( 30072576) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Hand grip strength ( 29691431) Reaction time ( 29844566) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 30224653)
Interacting Genes		40 interacting genes: ASCC3 ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	7 interacting genes: ASCC2 BARD1 BRCA1 HMGA1 PRMT5 RACK1 TUBG1
Entrez ID		84164	29789
HPRD ID		16515	15194
Ensembl ID		ENSG00000100325	ENSG00000138430
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	Q9NTK5
PDB IDs		2DI0	2OHF
Enriched GO Terms of Interacting Partners?
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