ASCC2 and ELAC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ASCC2	ELAC2
Description		activating signal cointegrator 1 complex subunit 2	elaC ribonuclease Z 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	Ubiquitin Binding	RNA Binding Endonuclease Activity TRNA-specific Ribonuclease Activity Metal Ion Binding
	Biological Process	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated	TRNA 3'-end Processing Mitochondrial TRNA 3'-trailer Cleavage, Endonucleolytic Mitochondrial TRNA Processing
Pathways		ALKBH3 mediated reversal of alkylation damage	tRNA processing in the nucleus tRNA processing in the mitochondrion rRNA processing in the mitochondrion
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Squamous cell lung carcinoma ( 28604730)
Interacting Genes		40 interacting genes: ASCC3 ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	8 interacting genes: ASCC2 CTBP1 CTBP2 CUX1 GOLM1 NDUFA7 RING1 SMAD2
Entrez ID		84164	60528
HPRD ID		16515	05641
Ensembl ID		ENSG00000100325	ENSG00000006744
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	A0A0S2Z5M8 Q9BQ52
PDB IDs		2DI0
Enriched GO Terms of Interacting Partners?
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