ASCC2 and TRIP4

Number of citations of the paper that reports this interaction (PubMedID 12077347)
38

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		ASCC2	TRIP4
Description		activating signal cointegrator 1 complex subunit 2	thyroid hormone receptor interactor 4
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex	Nucleus Nucleoplasm Cytoplasm Centrosome Cytosol Nuclear Body Neuromuscular Junction Protein-containing Complex Activating Signal Cointegrator 1 Complex
	Molecular Function	Ubiquitin Binding	Protease Binding Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Binding Protein Kinase Binding Estrogen Receptor Binding Histone Acetyltransferase Binding Ubiquitin-like Protein Ligase Binding
	Biological Process	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Intracellular Estrogen Receptor Signaling Pathway Regulation Of Myoblast Differentiation Positive Regulation Of Transcription, DNA-templated Toxin Transport
Pathways		ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)	Alzheimer's disease (late onset) ( 24162737) Neuroticism ( 29255261)
Interacting Genes		40 interacting genes: ASCC3 ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1	23 interacting genes: AR ASCC2 ASCC3 CREBBP EP300 ESR1 ESR2 GTF2A1 JUN NCOA1 NEK6 NFKB1 NR2F2 PAX9 PPARG RARA RELA RXRA SRF TBP THRB UBC XBP1
Entrez ID		84164	9325
HPRD ID		16515	05140
Ensembl ID		ENSG00000100325	ENSG00000103671
Uniprot IDs		A0A024R1E1 A0A024R1F9 Q9H1I8	Q15650
PDB IDs		2DI0	2E5O
Enriched GO Terms of Interacting Partners?
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