OLA1 and ASCC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
820

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OLA1	ASCC2
Description		Obg like ATPase 1	activating signal cointegrator 1 complex subunit 2
Image
GO Annotations	Cellular Component	Extracellular Region Nucleolus Cytoplasm Centrosome Cytosol Membrane Platelet Alpha Granule Lumen Extracellular Exosome	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	Protein Binding ATP Binding GTP Binding ATPase Activity Ribosome Binding Ribosomal Large Subunit Binding Cadherin Binding Metal Ion Binding	Ubiquitin Binding
	Biological Process	Platelet Degranulation ATP Metabolic Process	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated
Pathways		Platelet degranulation	ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Hand grip strength ( 29691431) Reaction time ( 29844566) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure ( 30224653)	Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		7 interacting genes: ASCC2 BARD1 BRCA1 HMGA1 PRMT5 RACK1 TUBG1	40 interacting genes: ASCC3 ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		29789	84164
HPRD ID		15194	16515
Ensembl ID		ENSG00000138430	ENSG00000100325
Uniprot IDs		Q9NTK5	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs		2OHF	2DI0
Enriched GO Terms of Interacting Partners?
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