BCAR3 and OSGIN1

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BCAR3	OSGIN1
Description		BCAR3 adaptor protein, NSP family member	oxidative stress induced growth inhibitor 1
Image			No pdb structure
GO Annotations	Cellular Component		Cellular_component
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	Protein Binding Growth Factor Activity
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Endothelin Receptor Signaling Pathway	Signal Transduction Multicellular Organism Development Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)	LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)
Interacting Genes		29 interacting genes: AGR3 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCL5 CST6 DKK3 EPSTI1 ERBB2 ERBB3 ERRFI1 GLCE GREB1 HOXC6 KPNA1 MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP VPS45	23 interacting genes: AKT1 ATM BCAR3 CAPN3 CCDC33 CRX DNAJA3 FGFR4 IKZF3 INCA1 KRAS LNX1 MEIS2 MEOX2 PPM1D PTEN REL SAXO1 SMARCB1 TCF12 TCF4 TLE5 XRCC3
Entrez ID		8412	29948
HPRD ID		05268	06412
Ensembl ID		ENSG00000137936	ENSG00000140961
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	Q9UJX0
PDB IDs		3T6A
Enriched GO Terms of Interacting Partners?
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