BCAR3 and BEX2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BCAR3	BEX2
Description		BCAR3 adaptor protein, NSP family member	brain expressed X-linked 2
Image			No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	Protein Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Endothelin Receptor Signaling Pathway	Apoptotic Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)
Interacting Genes		29 interacting genes: AGR3 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCL5 CST6 DKK3 EPSTI1 ERBB2 ERBB3 ERRFI1 GLCE GREB1 HOXC6 KPNA1 MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP VPS45	35 interacting genes: AURKA BCAR3 BLZF1 BRMS1 CALCOCO2 CCDC85B CEP70 FGFR2 FSD2 KRT15 KRT31 KRT38 KRT40 KRTAP10-8 KRTAP4-12 KRTAP5-9 LMO2 LZTS2 MAGEA11 MAGEA4 MIPOL1 MKRN3 NECAB2 OMP PIK3CA PNMA1 PPM1D PRDM14 PTPN11 SSX2IP TRAF1 TRAF2 TRIM27 TRIM42 ZDHHC17
Entrez ID		8412	84707
HPRD ID		05268	06484
Ensembl ID		ENSG00000137936	ENSG00000133134
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	Q9BXY8
PDB IDs		3T6A
Enriched GO Terms of Interacting Partners?
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