BCAR3 and PDLIM2

Number of citations of the paper that reports this interaction (PubMedID 25640309)
5

Data Source:
BioGRID (two hybrid)

		BCAR3	PDLIM2
Description		BCAR3 adaptor protein, NSP family member	PDZ and LIM domain 2
Image
GO Annotations	Cellular Component		Stress Fiber Nucleus Adherens Junction Z Disc Filamentous Actin
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Binding	Actin Binding Protein Binding Metal Ion Binding Muscle Alpha-actinin Binding
	Biological Process	Lens Morphogenesis In Camera-type Eye Signal Transduction Small GTPase Mediated Signal Transduction Insulin Receptor Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Response To Drug Positive Regulation Of MAPK Cascade Positive Regulation Of GTPase Activity Positive Regulation Of DNA Replication Endothelin Receptor Signaling Pathway	Heart Development Actin Cytoskeleton Organization Muscle Structure Development
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease progression score ( 29860282) Blood urea nitrogen levels ( 31152163) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Estimated glomerular filtration rate ( 31152163) Major depressive disorder ( 27777418) Systolic blood pressure ( 30224653)	Parkinson's disease ( 28892059) Survival in breast cancer (estrogen-receptor positive) ( 29423119)
Interacting Genes		29 interacting genes: AGR3 APP ATAD2 BAP1 BEX1 BEX2 CASZ1 CCL5 CST6 DKK3 EPSTI1 ERBB2 ERBB3 ERRFI1 GLCE GREB1 HOXC6 KPNA1 MTA3 NEDD9 NSD3 OSGIN1 PDLIM2 PRDM14 PSMC3IP RPRD1A SERPINB5 THRSP VPS45	12 interacting genes: ACD APC AURKA BAG4 BCAR3 FGFR2 FGFR4 MKRN2 POT1 RAF1 TGFB1 UBE2E2
Entrez ID		8412	64236
HPRD ID		05268	17831
Ensembl ID		ENSG00000137936	ENSG00000120913
Uniprot IDs		A0A384MTS3 B3KNL6 B3KP06 O75815	Q96JY6
PDB IDs		3T6A	2PA1 3PDV
Enriched GO Terms of Interacting Partners?
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